Manifest MedEx To Apply for Designation as a Qualified Health Information Organization (QHIO) in the California Health and Human Services Data Exchange Framework

Application Reinforces Nonprofit Health Data Network’s Commitment To Serve as Critical Health Data Infrastructure for All Californians

Emeryville, Calif. – (BUSINESS WIRE) – August 30, 2023 – Manifest MedEx (MX), California’s largest nonprofit health information organization (HIO), announced today it intends to apply for designation as a Qualified Health Information Organization (QHIO) in the California Health and Human Services Agency’s (CalHHS) Data Exchange Framework (DxF), a first-ever, statewide data-sharing agreement that will accelerate and expand the exchange of health information among healthcare entities, government agencies, and social service programs beginning in 2024.

A QHIO is an HIO that has demonstrated its ability to meet DxF data exchange requirements. Under California law passed in 2021, most healthcare organizations are required to share health data as defined by the DxF so that every resident in the state can benefit from seamlessly coordinated care and services regardless of where they live or seek care. For many healthcare organizations without the current technical capability to meet the DxF requirements, a QHIO can help them securely participate in the DxF as permitted and required.

“Manifest MedEx has long been committed to advancing interoperability and health data-sharing across California in service to patients and their care teams,” said Jarrod McNaughton, Board Chair of Manifest MedEx and Chief Executive Officer of Inland Empire Health Plan. “Becoming a QHIO is an important step in enabling and supporting the high-quality health data infrastructure our state needs to ensure all Californians get the care they need, and no one falls through the cracks.”

Manifest MedEx demonstrates the highest levels of security in the healthcare industry and has consistently earned HITRUST CSF® Certification since 2019. The nonprofit health data network securely shares permitted health data for approximately 37 million Californians — over 90% of Californians — across a network of more than 1,800 healthcare providers, 125 hospitals, and 13 health plans, including Aetna, Blue Shield of California, Anthem Blue Cross, Health Net, and Inland Empire Health Plan. A participant in eHealth Exchange and leveraging their connection to the Carequality Framework, Manifest MedEx provides millions of longitudinal health records every month to care teams at some of California’s largest health systems, including Kaiser Permanente and Sutter Health.

In 2021, Manifest MedEx was also designated as a QHIO under the California Health Information Exchange Onboarding Program (Cal-HOP), an incentive program created to help hospitals and providers participate in and share data through health information exchanges to improve the quality and effectiveness of care for Medi-Cal beneficiaries.

“We applaud the state for recognizing the importance of secure and robust health data exchange that is integral to advancing health and health equity for all Californians,” said Erica Galvez, Chief Executive Officer of Manifest MedEx. “We will continue to support all mandatory signatories under the DxF in their efforts to share and use health data to benefit individual Californians and the population as a whole. Earning the state’s QHIO designation will be an honor.”

Manifest MedEx also intends to participate in the Office of the National Coordinator’s (ONC’s) Trusted Exchange Framework and Common Agreement (TEFCA) exchange through eHealth Exchange.


About Manifest MedEx
As the largest nonprofit health data network in California, Manifest MedEx (MX) is an integral part of the state’s health data infrastructure, combining and delivering crucial health information for more than 37 million Californians across 125+ hospitals, 13 health plans, and over 1,800 providers. Together, we are transforming the healthcare landscape across the state, supporting California as a leader in equitable, affordable, proactive, and compassionate medical care. For more information, visit and follow us at @ManifestMedEx.

Media Contact
Sarita Choy
Manifest MedEx