Optimizing Health with High-Resolution Data

We connect and support local communities to advance whole person care.

Manifest MedEx is California’s largest nonprofit health data network. We securely bring together data to provide actionable clarity for coordinating health and powering an equitable future.

Our network ensures that when an individual needs care, their story is already there.

As a mission-driven non-profit organization, we focus on the hard-to-reach data—including behavioral health and social drivers of health (SDOH)—that traditional exchanges leave behind. We believe every individual and their care team should be able to rely on health data as a foundational resource: always accurate, highly secure, and seamlessly available.

Behind every record is a person. We power the infrastructure that makes moments of care seamless for everyone involved.

Manifest MedEx is:

TRUSTED

We lead with the expertise  needed to set the standard for state and national health transformation.

COMMUNITY-CENTERED

We bridge the gap between health, social care, behavioral health, and public health, rooted in the specific communities we serve.

MISSION-DRIVEN

Our work is guided by our  commitment to helping people and improving public health.

Our Mission: Connect and empower healthier communities

Our Vision: High-resolution data from Manifest MedEx optimizes health and value for all

Fast Facts


California’s largest nonprofit health data network.


State-designated QHIO serving every county in California.


SHIE connecting social care with clinical insights.


53 million individual records across clinical and claims data.


NCQA-validated data and 7-year organizational HITRUST certification.

Manifest MedEx’s mission is to connect and empower healthier communities. Our 2035 vision is that high-resolution data from Manifest MedEx optimizes health and value for all.

Manifest MedEx was formed in 2017 through the merger of Cal INDEX and IEHIE (Inland Empire Health Information Exchange).

Yes. Manifest MedEx is a 501(c)(3) nonprofit organization.

Erica Galvez is the CEO of Manifest MedEx, a role she has held since 2022. She has been with MX since its founding in 2017, previously serving as COO, Chief of Strategy, and Chief of Staff.

Manifest MedEx is a nonprofit funded primarily through participation fees paid by the healthcare organizations, health plans, and other entities that use our network, along with grant funding that supports specific initiatives.

Manifest MedEx is the largest nonprofit network for health data in California. MX is a leader in a national movement of health data utilities delivering both high resolution data (a complete, real-time view of a person’s care history pulled from multiple sources) and whole person data (connecting clinical information with social and community-based information) so providers and care teams can see the full picture of a person’s health.