Our Network

Advancing Statewide Connectivity to Support Whole Person Care

4000+

NETWORK PARTICIPANTS

190+

HOSPITALS

21

HEALTH PLANS

53M

INDIVIDUAL RECORDS

As California’s health data utility, Manifest MedEx (MX) exchanges clinical, behavioral, and social health data to ensure information is accessible for permitted teams to provide timely care based on a full picture of a person.

At the core of our work is a shared vision to advance health data interoperability and build a more connected and effective health system across the state – realized through partnerships and collaboration with health plans, hospitals, providers, and community stakeholders.

Whole person care starts with local insights.

MX Advisory Committee

The Advisory Committee assists MX in understanding the needs of our participants—aligning products, services, and policies with industry developments, and adopting best practices. The Committee is composed of experienced professionals representing a diverse cross-section of the health community—including hospitals, clinics, health plans, and community-based organizations.

MX Affiliate Program

The MX Affiliate Program offers the opportunity for regional health information exchanges in California to expand their technical capabilities and commitments to health information sharing within their communities. These affiliates help build the MX network by providing front-line support in connecting regional participants and guidance on the future direction meeting local needs.

Current affiliates:

Reach out to learn more if your HIO is interested in partnering with MX.

The Manifest MedEx network is California’s largest nonprofit health data network, connecting hospitals, health plans, ambulatory providers, counties, independent physician associations (IPAs), and community-based organizations to securely exchange clinical, claims, behavioral health, and social care data across every county in the state.

Manifest MedEx securely exchanges more than 53 million health records across a network of more than 4,000 organizations, including 190+ hospitals, 20+ health plans, 32 county and state agencies, and 3,200+ ambulatory providers.

MX participants include hospitals and health systems, health plans, IPAs and medical groups, ambulatory practices, county health and social service agencies, community-based organizations, and other health-related social services providers.

Participants can exchange permitted clinical, claims, behavioral health, and social care data, including admission, discharge, and transfer (ADT) notifications, longitudinal health records, lab results, medications, and social drivers of health information, supporting a whole-person view of each individual.

Yes. Manifest MedEx is a Qualified Health Information Organization (QHIO) under California’s Data Exchange Framework (DxF), and we are the largest nonprofit QHIO serving every county in the state. Manifest MedEx was also designated a QHIO under Cal-HOP in 2021. Cal-HOP was an incentive program created to help hospitals and providers participate in and share data through health information exchanges to improve the quality and effectiveness of care for Medi-Cal beneficiaries.

Yes. As a QHIO under California’s Data Exchange Framework, Manifest MedEx both delivers data on behalf of its participants and receives permitted health data from other QHIOs and DxF participants across the state. This allows MX participants to benefit from a broader statewide data-sharing ecosystem, not just the MX network itself.

Yes. Manifest MedEx was among the first health information organizations in the country to choose to connect to the Trusted Exchange Framework and Common Agreement™ (TEFCA®), doing so through eHealth Exchange’s designation as a QHIN (Qualified Health Information Network). MX also participates more broadly in national networks, including eHealth Exchange and Carequality. Together, these connections let MX participants securely exchange data with healthcare organizations across the country, not just within California.

Yes. On behalf of organizations that select Manifest MedEx as their DxF intermediary, Manifest MedEx can access data from other DxF signatories and QHIOs that aren’t direct MX network participants. MX also participates in national networks like eHealth Exchange and Carequality, which allows us to access and deliver clinical data from health systems outside the MX network entirely, including Kaiser Permanente and University of California medical centers. Together, these connections give MX participants a more complete picture of a person’s care history, even when care was received outside the MX network.

A QHIN (Qualified Health Information Network) is a national-level entity designated under the Trusted Exchange Framework and Common Agreement™ (TEFCA®) to facilitate health data exchange across the country. A QHIO (Qualified Health Information Organization) is a California-specific designation under the state’s Data Exchange Framework (DxF). Manifest MedEx is a QHIO and participates in TEFCA through its partnership with eHealth Exchange, a designated QHIN. This gives MX participants access to both state-level and national-level data exchange through a single connection.

A framework, like California’s Data Exchange Framework (DxF) or the national TEFCA®, is a set of rules, policies, and legal agreements that establish how healthcare organizations are permitted and required to share health data. A network, such as Manifest MedEx, is the operational infrastructure, the pipes, that actually exchanges the data, connecting organizations, moving records, and enabling real-time information sharing in compliance with those frameworks.

At Manifest MedEx the pipes and infrastructure are the foundation, and we have built additional capabilities from there. MX provides population health analytics and can also enhance or “uplift” data, mapping local or non-standard codes to standard codes to improve the accuracy of data and make it more actionable.

A national network, like eHealth Exchange or Carequality, is a system that connects healthcare organizations across the country to exchange health data. A QHIN (Qualified Health Information Network) is a formal designation, granted by the federal government to organizations that meet specific technical and security requirements to exchange data nationwide in accordance with the Trusted Exchange Framework and Common Agreement™ (TEFCA®). There are currently more than a dozen designated QHINs nationwide. Manifest MedEx participates in eHealth Exchange’s national network, and separately connects to TEFCA through eHealth Exchange’s designation as a QHIN, giving MX participants access to both traditional national network exchange and the newer TEFCA framework.

Manifest MedEx connects with 190+ hospitals across California.

Manifest MedEx connects with more than 20 health plans across California.

Manifest MedEx securely delivers an average of 3.3 million admission, discharge, and transfer (ADT) notifications each month, helping care teams respond quickly when a patient enters or leaves a hospital.

Organizations can learn more about joining the Manifest MedEx network and start the partnership process at manifestmedex.org/partner-with-mx.